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The natural history of aberrant crypt foci

✍ Scribed by Robert E. Schoen; Matthew Mutch; Christopher Rall; Sarah M. Dry; David Seligson; Asad Umar; Paul Pinsky

Book ID: 119245179
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 322 KB
Volume: 67
Category: Article
ISSN: 1097-6779
DOI: 10.1016/j.gie.2007.08.048

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## Abstract AKR/J mice are resistant to the tumorigenic properties of the colon carcinogen, azoxymethane (AOM). Following AOM exposure, limited numbers of preneoplastic lesions, referred to as aberrant crypt foci (ACF), are formed in the colon, and their progression to tumors rarely occurs. To dete