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The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth

✍ Scribed by Daniela Roell; Aria Baniahmad


Book ID
116734887
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
488 KB
Volume
332
Category
Article
ISSN
0303-7207

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## Abstract We have reported that nordihydroguaiaretic acid (NDGA) inhibits the tyrosine kinase activities of the IGF‐1 receptor (IGF‐1R) and the HER2 receptor in breast cancer cells. Herein, we studied the effects of NDGA on the growth of estrogen receptor (ER) positive MCF‐7 cells engineered to o