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The natriuretic peptide receptors are present in human and canine cardiac fibrobalsts

✍ Scribed by Sharon M. Sandberg; Brenda K. Huntley; Alessandro Cataliotti; John C. Burnett

Book ID: 119588724
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 53 KB
Volume: 9
Category: Article
ISSN: 1532-8414
DOI: 10.1016/s1071-9164(03)00470-6

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## Abstract Cardiac remodeling involves the accumulation of extracellular matrix (ECM) proteins including fibronectin (FN). FN contains RGD motifs that bind integrins at DDX sequences allowing signaling from the ECM to the nucleus. We noted that the natriuretic peptide receptor A (NPR‐A) sequence c