The human tyrosine aminotransferase gene
✍
Eva-Maria Westphal; Ernst Natt; Tiemo Grimm; Michel Odievre; Gerd Scherer
📂
Article
📅
1988
🏛
Springer
🌐
English
⚖ 532 KB
Deficiency in hepatic tyrosine aminotransferase (TAT) causes tyrosinemia type II, an autosomal recessively inherited disorder. Using a TAT cosmid clone, we have identified an MspI restriction fragment length polymorphism (RFLP) 5' to the TAT gene, with allele frequencies of 0.63 and 0.37. Analysis o