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The muscarinic agonist pilocarpine inhibits DNA and interferon-γ synthesis in peripheral blood mononuclear cells

✍ Scribed by E.S. Arzt; Silvia Fernández-Castelo; A. Diaz; S. Finkielman; V.E. Nahmod


Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
474 KB
Volume
11
Category
Article
ISSN
0192-0561

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The treatment of choice for patients infected chronically with HCV is the combination of IFN-alpha and ribavirin. Monotherapy with ribavirin leads to a clinical and histological improvement, but its exact mechanism of action is unknown. Therefore, the effect of ribavirin on synthesis of inflammatory