The murine local lymph node assay for identification of contact allergens: a preliminary evaluation of in situ measurement of lymphocyte proliferation
โ Scribed by Ian Kimber; Jennifer Hilton; Claudia Weisenberger
- Book ID
- 109369130
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 611 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0105-1873
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๐ SIMILAR VOLUMES
A modified version of the local lymph node assay (LLNA) is presented, using bromodeoxyuridine to label proliferating lymphocytes. Cell counting is done on mid-sagittal sections of individual nodes under light microscopy. Two irritants (sodium lauryl sulfate and salicylic acid), four allergens of var
A murine local lymph node assay has been developed for the identification of contact sensitizing chemicals. In the present study, the performance of the local lymph node assay has been evaluated with twenty-four coded chemicals of previously unknown skin sensitizing potential and the results compar