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The MTHFR C677T polymorphism modifies age at onset in Parkinson’s disease

✍ Scribed by Vallelunga, Annamaria; Pegoraro, Valentina; Pilleri, Manuela; Biundo, Roberta; Iuliis, Angela; Marchetti, Mauro; Facchini, Silvia; Formento Dojot, Patrizia; Antonini, Angelo

Book ID
121373924
Publisher
Springer Milan
Year
2013
Tongue
English
Weight
188 KB
Volume
35
Category
Article
ISSN
1590-1874

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## Abstract Different lines of evidence indicate that methylenetetrahydrofolate reductase (__MTHFR__) functional gene polymorphisms, causative in aberrant folate–homocysteine metabolism, are associated with increased vulnerability to several heritable developmental disorders. Opposing views are exp