## Abstract Different lines of evidence indicate that methylenetetrahydrofolate reductase (__MTHFR__) functional gene polymorphisms, causative in aberrant folate–homocysteine metabolism, are associated with increased vulnerability to several heritable developmental disorders. Opposing views are exp
✦ LIBER ✦
Methylenetetrahydrofolate reductase ( MTHFR ) C677T polymorphism and age at onset of schizophrenia: No consistent evidence for an association in the nordic population
✍ Scribed by Saetre, Peter; Grove, Jakob; Børglum, Anders D.; Mors, Ole; Werge, Thomas; Andreassen, Ole A.; Vares, Maria; Agartz, Ingrid; Terenius, Lars; Jönsson, Erik G.
- Book ID
- 118751232
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 132 KB
- Volume
- 159B
- Category
- Article
- ISSN
- 1552-4841
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Methylenetetrahydrofolate reductase (MTHFR) is involved in the one-carbon cycle, which is of importance for nucleotide synthesis and methylation of DNA, membranes, proteins and lipids. The MTHFR gene includes two common polymorphisms (rs1801133 or C677T; rs1801131 or A1298C) which both alter enzyme
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