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The molecular mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons

โœ Scribed by Michael S. Denison


Book ID
116078662
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
274 KB
Volume
23
Category
Article
ISSN
0045-6535

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We studied the response t o 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) of mouse hepatoma cells that contain a single, integrated copy o f a chimeric gene under the control of a dioxin-responsive DNA domain, which was originally associated with the cytochrome P450/A 7 gene. Our findings indicate that