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The molecular basis of the structure and function of the 5-HT 3 receptor: a model ligand-gated ion channel (Review)

✍ Scribed by Reeves, David C.; Lummis, Sarah C. R.


Book ID
118268880
Publisher
Informa plc
Year
2002
Tongue
English
Weight
623 KB
Volume
19
Category
Article
ISSN
0968-7688

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ChemInform Abstract: A New 5-HT3 Recepto
✍ M. YAMADA; Y. SATO; K. KOBAYASHI; F. KONNO; T. SONEDA; T. WATANABE πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 2 views

Several substituted 2-pyridazinyl benzoxazole derivatives (VII), (VIII) and (IX) are prepared and evaluated for their utility as 5-HT 3 receptor agonists. A detailed structure-activity relationship study is presented. The most promising results are obtained for the derivatives (VIIa), (VIId) and (VI