The molecular basis of rheumatoid arthritis
✍ Scribed by C. M. Weyand; Jörg J. Goronzy
- Book ID
- 105797346
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 444 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0946-2716
No coin nor oath required. For personal study only.
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Susceptibility to rheumatoid arthritis (RA) maps to residues QKRAA/QRRAA in the third hypervariable region of the HLA DRI31 chain. Peptides from the same area of MHC class II molecules are able to modulate the T-cell repertoire by deleting self-reactive T-cells. The Epstein Barr virus glycoprotein g
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