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The molecular basis of common and rare fragile sites

✍ Scribed by Michal Schwartz; Eitan Zlotorynski; Batsheva Kerem

Book ID: 116333921
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 292 KB
Volume: 232
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2005.07.039

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## Abstract Common chromosome fragile sites occur at specific sequences within mammalian genomes that exhibit apparent single‐stranded regions in mitotic chromosomes on exposure of cells to replication stress. Recent progress in the characterization of sequences, and more precise mapping of common