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The molecular basis for cross-reaction of an anti-dystrophin antibody with alpha-actinin

✍ Scribed by Marian James; Nguyen thi Man; Yvonne H. Edwards; Glenn E. Morris


Book ID
117618185
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
792 KB
Volume
1360
Category
Article
ISSN
0925-4439

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## Abstract The onset of autoimmune diseases is proposed to involve binding promiscuity of antibodies (Abs) and T‐cells, an often reported yet poorly understood phenomenon. Here, we attempt to approach two questions: first, is binding promiscuity a general feature of monoclonal antibodies (mAbs) an