Molecular basis for the binding polyspec
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Livia Otte; Tobias Knaute; Jens Schneider-Mergener; Achim Kramer
📂
Article
📅
2005
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John Wiley and Sons
🌐
English
⚖ 448 KB
## Abstract The onset of autoimmune diseases is proposed to involve binding promiscuity of antibodies (Abs) and T‐cells, an often reported yet poorly understood phenomenon. Here, we attempt to approach two questions: first, is binding promiscuity a general feature of monoclonal antibodies (mAbs) an