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The modulatory influence of polymorphism of the serotonin transporter gene on characteristics of mental maladaptation in relatives of patients with endogenous psychoses

✍ Scribed by M. V. Alfimova; V. E. Golimbet; G. I. Korovaitseva; T. V. Lezheiko; L. I. Abramova; V. G. Kaleda; A. N. Barkhatova


Publisher
Springer US
Year
2008
Tongue
English
Weight
121 KB
Volume
38
Category
Article
ISSN
0097-0549

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The beta-2-adrenergic receptor (beta(2-)-AR) has several single-nucleotide polymorphisms. These influence the functional response to adrenergic stimulation; genotypes homozygous for Gly16-Glu27 or Gly16-Gln27 alleles (Gly16-Glu/Gln27 haplotypes) are associated with enhanced response, whereas genotyp