It has been suggested that the serotonin transporter (5-hydroxytryptamine-transporter or 5-HTT) may be involved in the pathogenesis of affective disorders. Recently, Collier et al. (1996) found that the frequency of the low-activity short variant (s) of the 5-HTT-linked polymorphic region (5-HTTLPR)
β¦ LIBER β¦
Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder
β Scribed by Heon-Jeong Lee; Min-Soo Lee; Rhee-Hun Kang; Hyun Kim; Soon-Duck Kim; Baik-Seok Kee; Young Hoon Kim; Yong-Ku Kim; Jung Bum Kim; Byung Kil Yeon; Kang Seob Oh; Byung-Hoon Oh; Jin-Sang Yoon; Chul Lee; Han Yong Jung; Ik-Seung Chee; In Ho Paik
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 85 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1091-4269
- DOI
- 10.1002/da.20064
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Bipolar disorder is a major psychiatric illness that has evidence for a significant genetic contribution toward its development. In recent years, the BalI RFLP (restriction fragment length polymorphism) in the dopamine D3 receptor gene has been examined as a possible susceptibility factor for both s