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The mitochondrial stress protein HSP60 as a catalyst of protein folding

โœ Scribed by HARTL, F; MARTIN, J; OSTERMANN, J; HORWICH, A; NEUPERT, W


Book ID
122262360
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
151 KB
Volume
14
Category
Article
ISSN
0309-1651

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## Abstract The 90 kDa heat shock proteins (Hsp90) are responsible for the conformational maturation of nascent polypeptides and the renaturation of denatured proteins. In transformed cells, numerous mutated and overexpressed proteins rely on the Hsp90 protein folding machinery for tumor progressio