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The Microglial K+ Channels Kv1.3 and KCa3.1 as Potential Therapeutic Targets for Ischemic Stroke

✍ Scribed by Wulff, Heike; Chen, Yi-Je; Jenkins, Paul D.; Nguyen, Hai; Garing, April L.; Köhler, Ralf

Book ID
122490170
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
49 KB
Volume
106
Category
Article
ISSN
0006-3495

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The lymphocyte potassium channels Kv1.3
The lymphocyte potassium channels Kv1.3 and KCa3.1 as targets for immunosuppression
✍ Jenny Lam; Heike Wulff 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

## Abstract The voltage‐gated Kv1.3 and the calcium‐activated KCa3.1 potassium channel modulate many calcium‐dependent cellular processes in immune cells, including T‐cell activation and proliferation and have therefore been proposed as novel therapeutic targets for immunomodulation. Kv1.3 is highl