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The methylation pattern of p16INK4a gene promoter in psoriatic epidermis and its clinical significance

โœ Scribed by M. Chen; Z-Q. Chen; P-G. Cui; X. Yao; Y-M. Li; A-S. Li; J-Q. Gong; Y-H. Cao

Book ID
108669986
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
392 KB
Volume
158
Category
Article
ISSN
0007-0963

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## Abstract Loss of p16^INK4a^ protein expression has frequently been related to DNA methylation in association with gene silencing. Although the methylation status of exon1ฮฑ for p16^INK4a^ involvement in various cancers has been extensively analyzed, it has been pointed out that some inconsistenci