𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus

✍ Scribed by N. M. Dixit; A. S. Perelson


Publisher
Springer
Year
2006
Tongue
English
Weight
548 KB
Volume
63
Category
Article
ISSN
1420-682X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Antiviral activity of aucubin against he
✍ Il-Moo Chang πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 91 KB πŸ‘ 2 views

Aucubin, an iridoid glycoside was found to suppress hepatitis B virus DNA replication in vitro in a 2.2.15 cell culture system. Aucubin itself did not exhibit antiviral activity, but it showed significant activity when preincubated with ␀-glucosidase. Aucubin possesses no cytotoxicity at a broad ran

Antiviral activity of 2,3β€²-anhydro and r
✍ Naveen C. Srivastav; Michelle Mak; Babita Agrawal; D. Lorne J. Tyrrell; Rakesh K πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 264 KB

Various 2,3'-anhydro analogs of 5-substituted 1-(2-deoxy-Ξ²-d-lyxofuranosyl)uracils (10-15) and a related 1-(3-O-mesyl-2-deoxy-Ξ²-d-lyxofuranosyl) pyrimidine nucleoside analog (18) have been synthesized for evaluation as a new class of potential anti-HBV agents. The compounds 10, 12, and 15 demonstrat

Antiviral activity of the hepatitis C vi
✍ Frank Wagner; Robert Thompson; Constantino Kantaridis; Paul Simpson; Philip J. F πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 599 KB

More effective and better-tolerated therapies are needed for chronic hepatitis C virus (HCV) infection. Among the direct-acting anti-HCV agents in development is the nonstructural 5B protein (NS5B polymerase) non-nucleoside inhibitor filibuvir. We investigated the antiviral activity, pharmacokinetic

Biliverdin inhibits hepatitis C virus no
✍ Zhaowen Zhu; Anne T. Wilson; Bruce A. Luxon; Kyle E. Brown; M. Meleah Mathahs; S πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 882 KB

Induction of heme oxygenase-1 (HO-1) inhibits hepatitis C virus (HCV) replication. Of the products of the reaction catalyzed by HO-1, iron has been shown to inhibit HCV ribonucleic acid (RNA) polymerase, but little is known about the antiviral activity of biliverdin (BV). Herein, we report that BV i