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The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

✍ Scribed by Brandon S Pybus, Sean R Marcsisin, Xiannu Jin, Gregory Deye…

Book ID
120685576
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
304 KB
Volume
12
Category
Article
ISSN
1475-2875

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## Abstract ## Objective Risperidone is converted to 9‐hydroxyrisperidone by CYP2D6. Two parameters were used to examine the influences of CYP2D6 polymorphism and of co‐medication on risperidone metabolism: the risperidone:9‐hydroxyrisperidone concentration ratio (R:9‐OHR ratio) and the sum of the