The metabolism of ethylene dibromide in the rat: The enzymic reaction with glutathione in vitro and in vivo
โ Scribed by Edna Nachtomi
- Book ID
- 115770336
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- English
- Weight
- 570 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0006-2952
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๐ SIMILAR VOLUMES
The nematocide, grain fumigant, and gasoline additive 1,2-dibromoethane (DBE) is both a cellular and a genetic toxin that is metabolically activated in rats and mice by mixed function oxidases (MFO) as well as glutathione S-transferases (GST). The purpose of this study was to determine whether DBE i
Fenobam [(Fn); N-(3-chlorophenyl)-N-(4,5-dihydro-l -methyl-4-0x0-1 Kimidazole-2-yl)urea] sulfate is a novel agent with potent anxiolytic activity in rats. [14C]Fn sulfate was administered as an oral solution (250 mglkg) to male Wistar rats, and 52% of the administered dose was excreted in urine (0-5