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In vivo and in vitro metabolism of ethylenethiourea in the rat and the cat

โœ Scribed by F. Iverson; K.S. Khera; S.L. Hierlihy


Book ID
116072687
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
427 KB
Volume
52
Category
Article
ISSN
0041-008X

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Fenobam [(Fn); N-(3-chlorophenyl)-N-(4,5-dihydro-l -methyl-4-0x0-1 Kimidazole-2-yl)urea] sulfate is a novel agent with potent anxiolytic activity in rats. [14C]Fn sulfate was administered as an oral solution (250 mglkg) to male Wistar rats, and 52% of the administered dose was excreted in urine (0-5