The metabolism of articular cartilage in osteoarthritis
β Scribed by H. Telhag; A. Hulth; L. Lindberg
- Publisher
- Springer
- Year
- 1970
- Tongue
- English
- Weight
- 55 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1432-0827
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We report the use of immunologic methods for detecting specific alterations in human osteoarthritic cartilage. Monoclonal antibodies with specificities for proteoglycans and link proteins have been used to define immunogenic sites in these molecules. We have identified 1 site in the protein core, 1
## Abstract ## Objective To investigate the in vivo effects of dehydroepiandrosterone (DHEA) on knee joints during the development of experimentally induced osteoarthritis (OA). ## Methods Twentyβtwo mature NZW rabbits underwent bilateral anterior cruciate ligament transection (ACLT) and receive