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The Mechanisms of Substitution of Propargylic Halides. 3-Bromo-3-methyl-1-butyne

✍ Scribed by Shiner, V. J.; Wilson, Joseph W.

Book ID
127283181
Publisher
American Chemical Society
Year
1962
Tongue
English
Weight
948 KB
Volume
84
Category
Article
ISSN
0002-7863

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## Abstract Isoquinolinones were brominated using __N__‐bromosuccinimide in dimethylformamide at room temperature to give 4‐bromo‐3‐substituted isoquinolin‐1‐(2__H__)‐ones. The reaction of these isoquinolinones with propargyl bromide in the presence of anhydrous potassium carbonate yielded __N__ an