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The mechanisms of sarcoplasmic reticulum Ca2+ release in toad pacemaker cells

✍ Scribed by Yue-Kun Ju; David G. Allen

Book ID
111119368
Publisher
Cambridge University Press
Year
2000
Tongue
English
Weight
241 KB
Volume
525
Category
Article
ISSN
0022-3751

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Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an