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The mechanism of telomere protection: a comparison betweenDrosophilaand humans

✍ Scribed by Giovanni Cenci; Laura Ciapponi; Maurizio Gatti

Book ID
106089887
Publisher
Springer
Year
2005
Tongue
English
Weight
268 KB
Volume
114
Category
Article
ISSN
0009-5915

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## Abstract Two types of telomere maintenance mechanisms (TMMs) have been described in human tumors: telomerase activation and alternative lengthening of telomeres (ALT). Although the vast majority of epithelial tumors rely on telomerase activation, many mesenchymal tumors rely on ALT for telomere