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The mechanism of sugar phosphate isomerization by glucosamine 6-phosphate synthase

✍ Scribed by Alexei Teplyakov; Galya Obmolova; Marie-Ange Badet-Denisot; Bernard Badet


Book ID
111753593
Publisher
Cold Spring Harbor Laboratory Press
Year
2008
Tongue
English
Weight
531 KB
Volume
8
Category
Article
ISSN
0961-8368

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ChemInform Abstract: Design, Synthesis,
✍ F. MASSIERE; M.-A. BADET-DENISOT; L. RENE; B. BADET πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 27 KB πŸ‘ 2 views

Design, Synthesis, and Evaluation of the First Mechanism-Based Inhibitor of Glucosamine 6-Phosphate Synthase. -The first example of the title inhibitor, the compound (I), a glutamine derivative bearing a latent electrophilic function, is prepared starting from suitably protected glutamine. (I) is st