𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Mechanism of Catalytic Enantioselective Fluorination: Computational and Experimental Studies

✍ Scribed by Stefano Piana; Ingrid Devillers; Antonio Togni; Ursula Rothlisberger


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
129 KB
Volume
41
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The Mechanism of Catalytic Enantioselect
✍ Stefano Piana; Ingrid Devillers; Antonio Togni; Ursula Rothlisberger πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 129 KB πŸ‘ 2 views

Despite the undisputed importance of organofluorine compounds, for example, in biomedical applications, the generation of fluorinated carbon stereocenters by CΓ€F bond-forming reactions remains rare and particularly challenging. [1, 2] Recently, the first catalytic, enantioselective fluorination of b

Computational studies of the domain move
✍ Steven W. Rick; Yuri G. Abashkin; Richard L. Hilderbrandt; Stanley K. Burt πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 400 KB πŸ‘ 1 views

Thymidine phosphorylase (TP) is a dual substrate enzyme with two domains. Each domain binds a substrate. In the crystal structure of Escherichia coli TP, the two domains are arranged so that the two substrate binding sites are too far away for the two substrates to directly react. Molecular dynamics