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Enantioselective and Diastereoselective Tsuji–Trost Allylic Alkylation of Lactones: An Experimental and Computational Study

✍ Scribed by Dr. Panos Meletis; Dr. Mahendra Patil; Prof. Dr. Walter Thiel; Prof. Dr. Walter Frank; Prof. Dr. Manfred Braun


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
313 KB
Volume
17
Category
Article
ISSN
0947-6539

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ChemInform Abstract: Enantioselective Co
✍ Ruben Manzano; Jose M. Andres; Rosana Alvarez; Maria D. Muruzabal; Angel R. de L 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 63 KB

## Abstract The L‐valine based thiourea VTU catalyzes the reaction of nitromethane with chalcones with up to 90% enantioselectivities, whereas ketones such as (Ih)‐(Ij) give only low enantioselectivities.