The mechanism of action of transforming growth factor-β
✍ Scribed by Miyazono, Kohei ;Heldin, Carl-Henrik
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 578 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0435-1339
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Transforming growth factors (TGFs) are growth‐promoting polypeptides that cause phenotypic transformation and anchorage‐independent growth of normal cells. They have been isolated from several human and animal carcinoma and sarcoma cells. One TGF is sarcoma growth factor (SGF) which is
JORMA KESKI-OJA Two types of transforming growth factors (TGF) have been purified and well characterized, TGFa and TGFP. TGFa is a 5.6 kD single chain molecule that shows sequence homology to epidermal growth factor (EGF), binds to the EGF receptor, and has biological effects very similar to those o
growth factor @, inhibits epidermal growth factor receptor endocytosis and down-regulation in cultured fetal rat hepatocytes.