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The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

✍ Scribed by Stedman, H. H.; Sweeney, H. L.; Shrager, J. B.; Maguire, H. C.; Panettieri, R. A.; Petrof, B.; Narusawa, M.; Leferovich, J. M.; Sladky, J. T.; Kelly, A. M.

Book ID
109777844
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
614 KB
Volume
352
Category
Article
ISSN
0028-0836

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The mdx mouse has a genetically homologous disease to Duchenne muscular dystrophy in humans. The disease progression, however, is not accompanied by the same level of fatty infiltration and muscle degeneration as occurs in humans. Thus, the presence of histological/ pathological changes in living md