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Animal Models of Duchenne Muscular Dystrophy, with Special Reference to the mdx Mouse

✍ Scribed by Alison, Blain; Elizabeth, Greally; Steve, Laval; Andrew, Blamire; Guy, Macgowan; Volker, Straub


Book ID
122889575
Publisher
Elsevier
Year
2012
Tongue
English
Weight
82 KB
Volume
32
Category
Article
ISSN
0208-5216

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The mdx mouse has a genetically homologous disease to Duchenne muscular dystrophy in humans. The disease progression, however, is not accompanied by the same level of fatty infiltration and muscle degeneration as occurs in humans. Thus, the presence of histological/ pathological changes in living md