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The Matrix Stiffness Regulates Morphology, Direction and Persistence of Motiles Cells

โœ Scribed by Riaz, Maryam; Versaevel, Marie; Gabriele, Sylvain


Book ID
122104467
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
66 KB
Volume
104
Category
Article
ISSN
0006-3495

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Matrix stiffness (resistance to deformation), one of the many mechanical forces acting on cells, is increasingly appreciated as an important mediator of cell behavior. It regulates cell signaling broadly, with effects on growth, survival, and motility. Although the stiffness optima for different kin