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THE MARTIN-BELL SYNDROME: A PSYCHOLOGICAL, LOGOPAEDIC AND CYTOGENETIC STUDY OF TWO AFFECTED BROTHERS

✍ Scribed by W. O. Renier; D. F. C. M. Smeets; J. M. J. C. Scheres; T. W. J. Hustinx; C. F. C. Hulsmans; C. P. M. O. Ophey; A. J. A. M. Bomers; F. J. M. Gabreëls


Book ID
114739984
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
439 KB
Volume
27
Category
Article
ISSN
0964-2633

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We analyzed the possibility of inherited predisposition to nondisjunction in a family with two cases of Down syndrome using restriction fragment length polymorphisms and cytogenetic heteromorphisms. In both patients the extra chromosome 21 was the result of a nondisjunction event at first meiotic di