Study of the origin of nondisjunction in
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Stinissen, Piet ;Van Roy, Bernadette ;Van Camp, Guy ;Backhovens, Hubert ;Partoen
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Article
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2005
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John Wiley and Sons
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English
⚖ 400 KB
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We analyzed the possibility of inherited predisposition to nondisjunction in a family with two cases of Down syndrome using restriction fragment length polymorphisms and cytogenetic heteromorphisms. In both patients the extra chromosome 21 was the result of a nondisjunction event at first meiotic di