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The mammalian Mediator complex and its role in transcriptional regulation

✍ Scribed by Ronald C. Conaway; Shigeo Sato; Chieri Tomomori-Sato; Tingting Yao; Joan W. Conaway


Book ID
113931177
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
124 KB
Volume
30
Category
Article
ISSN
0968-0004

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## Abstract Mammalian target of rapamycin (mTOR) is a protein serine‐threonine kinase that functions as a central element in signaling pathway involved in control of cell growth and proliferation. mTOR exists in at least two distinct multi‐protein complexes, mTORC1 and mTORC2. mTOR kinase controls