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The LPS- and PMA-induced expression of interleukin-1α and β mRNAs are controlled by multiple mechanisms

✍ Scribed by Woolman, K J


Book ID
122035681
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
169 KB
Volume
1
Category
Article
ISSN
1043-4666

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Neutrophils are possibly involved in the pathogenesis of various lung diseases through the release of numerous mediators. In the present study, we studied the regulation of IL-8 gene induction and protein secretion in human blood neutrophils. Northern blot analysis revealed that LPS increased IL-8 m