𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The local lymph node assay and the assessment of relative potency: status of validation

✍ Scribed by David A. Basketter; Frank Gerberick; Ian Kimber

Book ID
109376284
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
143 KB
Volume
57
Category
Article
ISSN
0105-1873

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Assessment of the relative skin sensitiz
Assessment of the relative skin sensitization potency of siloranes and bis-GMA using the local lymph node assay and QSAR predicted potency
✍ E.L. Kostoryz; Q. Zhu; H. Zhao; M. Miller; J.D. Eick 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 148 KB

## Abstract Siloranes are silicon and oxirane (epoxy) containing monomers used for new dental composite development. The siloranes 3,4‐epoxycyclohexylethyl‐cyclopolymethylsiloxane (Tet‐Sil) and bis‐3,4‐epoxycyclohexylethyl‐phenyl‐methylsilane (Ph‐Sil) have in common cycloaliphatic epoxy moieties. T

Assessment of the skin sensitization pot
Assessment of the skin sensitization potency of eugenol and its dimers using a non-radioisotopic modification of the local lymph node assay
✍ Masahiro Takeyoshi; Shuji Noda; Shunsuke Yamazaki; Hiroshi Kakishima; Kanji Yama 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB

## Abstract Allergic contact dermatitis is a serious health problem. There is a need to identify and characterize skin sensitization hazards, particularly with respect to relative potency, so that accurate risk assessments can be developed. For these purposes the murine local lymph node assay (LLNA

The local lymph node assay: Results of a
The local lymph node assay: Results of a final inter-laboratory validation under field conditions
✍ E. W. Scholes; D. A. Basketter; A. E. Sarll; I. Kimber; C. D. Evans; K. Miller; 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 578 KB

The local lymph node assay (LLNA) assesses the sensitizing activity of chemicals by measurement of primary lymphocyte proliferation in lymph nodes draining the site of application. In this final inter-laboratory study the consistency of LLNA results between laboratories and with guinea pig maximizat

Comparison of mouse strains using the lo
Comparison of mouse strains using the local lymph node assay
✍ Michael R Woolhiser; Albert E Munson; B.Jean Meade 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 78 KB

The local lymph node assay (LLNA), as recommended by the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), only allows for the use of CBA mice. The objective of these studies was to begin to assess the response of chemical sensitizers in the LLNA across six strain