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The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells

✍ Scribed by Chih-pin Chuu; Rou-Yu Chen; Richard A. Hiipakka; John M. Kokontis; Karen V. Warner; Jialing Xiang; Shutsung Liao

Book ID: 116294708
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 400 KB
Volume: 357
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2007.03.116

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## Abstract We previously demonstrated that ectopic expression of neurotrophic peptide (NP) derived from saposin C promotes androgen receptor (AR) expression and transactivation in human prostate cancer cells. This prompted us to investigate how NP or saposin C can function in cells. We constructed