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The lipophilicity estimation of 5-arylidene derivatives of (2-thio)hydantoin with antimycobacterial activity

✍ Scribed by Dorota Łażewska; Piotr Maludziński; Ewa Szymańska; Katarzyna Kieć-Kononowicz


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
185 KB
Volume
21
Category
Article
ISSN
0269-3879

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Estimating the lipophilicity of a number
✍ Elżbieta Pękala; Henryk Marona 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 134 KB 👁 1 views

## Abstract The lipophilicity of a number of __N__‐acyl derivatives of __trans__‐ or __cis__‐: racemic, (1__R__,2__R__)‐ or (1__S__,2__S__)‐aminocyclohexanol (1–13) exhibiting anticonvulsant activity was investigated. Their lipophilicity (__R__~m0~) was determined using reversed‐phase thin‐layer ch