## Abstract Cisplatin (CPT) is an effective anticancer drug that causes cumulative toxicity to normal tissues. It has been suggested that CPT damages normal cells by causing oxidative stress, but it is not known whether it can induce similar oxidative damage to tumor cells. In this study, by using
The lipids of normal diploid (WI-38) and sv40-transformed human cells
β Scribed by Barbara V. Howard; David Kritchevsky
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- French
- Weight
- 646 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Nineteen cultures of human embryonic or adult-tissue cells were exposed to sv40 as primary cultures or developed cell strains in Phase I1 of cultural life; 12 cultures were exposed to virus in Phase 111, at the end of in vitl-o life. After the expected proliferative response, infected cultures exhib
Assessment of the respiratory and glycolytic capacity of non-growing WI-38 cells shows that, in the absence and presence of added glucose, the mean rates of oxygen consumption were 247 (QOz = 5.61) and 208 (QOz = 4.73) mpmoles/mg dry wt/hr., respectively. Mean glucose consumption was 225 mpmoles/mg
## Abstract The mechanism of glucose entry into human vascular endothelial cells was studied in monolayer cultures of normal (primary) and virally (SV40) transformed umbilical vein endothelium. Radioisotopic uptake studies with the glucose analogues 2βdeoxyβDβglucose, and 3βOβmethylβDβglucose, and
## Abstract The proliferative activity of diploid human WIβ38 cells in sparse cultures depends on the extracellular concentration of free (or physiologically available) calcium, and cultivation in a medium having a calcium concentration of 0.1 mM or less gradually, but reversibly, arrest their prol