Growth plate chondrocytes make TGF-1 in latent form (LTGF-1) and store it in the extracellular matrix via LTGF-1 binding protein (LTBP1). 1,25-(OH) 2 D 3 (1,25) regulates matrix protein production in growth zone (GC) chondrocyte cultures, whereas 24,25-(OH) 2 D 3 (24,25) does so in resting zone (
The Latent-TGFβ-Binding-Protein-1 (LTBP-1) Is Expressed in the Organizer and Regulates Nodal and Activin Signaling
✍ Scribed by Curtis R. Altmann; Chenbei Chang; Ignacio Muñoz-Sanjuán; Esther Bell; Michael Heke; Daniel B. Rifkin; Ali H. Brivanlou
- Book ID
- 115599052
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 760 KB
- Volume
- 248
- Category
- Article
- ISSN
- 0012-1606
No coin nor oath required. For personal study only.
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