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The Lack of an Ovarian Effect of Lifetime Talc Exposure in F344/N Rats and B6C3F1 Mice

โœ Scribed by G.A. Boorman; J.C. Seely

Book ID
115646485
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
86 KB
Volume
21
Category
Article
ISSN
0273-2300

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Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr