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The kinase insert domain of colony stimulating factor-1 receptor is dispensable for CSF-1 induced phosphatidylcholine hydrolysis

โœ Scribed by Goutam Ghosh Choudhury; Victor L. Sylvia; Ling-Mei Wang; Jacalyne Pierce; Alan Y. Sakaguchi


Book ID
115924826
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
488 KB
Volume
282
Category
Article
ISSN
0014-5793

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Treatment of murine peritoneal exudate macrophages (PEM) by tumor-prornoting phorbol esters (TPA) results in a rapid loss of binding activity to radioactive-labeled colony-stimulating factor ([1251]-CSF-1) on the cell surface. The inhibitory effect of TPA on PEM i s transient; treated cells recover