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The Katsuki-Sharpless asymmetric epoxidation of (E)-2,5-dihydroxy-2,5-dimethyl-3-hexene

โœ Scribed by Seiichi Takano; Yoshiharu Iwabuchi; Kunio Ogasawara


Book ID
103401396
Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
129 KB
Volume
32
Category
Article
ISSN
0040-4039

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Application of Sharpless asymmetric epox
โœ Hong-yu Tian; Bao-guo Sun; Li-wei Tang; Hong-lin Ye ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 207 KB

## Abstract Optically active 2,3โ€epoxyhexanol obtained from Sharpless asymmetric epoxidation (AE) was regioselectively reduced to 1,3โ€hexandiol or 1,2โ€hexandiol. 1,3โ€Hexandiol was converted to 3โ€mesyloxyhexyl acetate. The following reaction with CH~3~SK gave 3โ€methylthiohexanol, which was oxidized