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The karyotype evolution in chronic granulocytic leukaemia—II. The chromosome and karyotype pattern of advanced evolution

✍ Scribed by Bent Pedersen

Book ID
113145420
Publisher
Elsevier Science
Year
1973
Weight
400 KB
Volume
9
Category
Article
ISSN
0014-2964

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The study of chromosome banding pattern of leukaemic cells in 15 patients with CML revealed t(9;22) in all cases. Similar additional chromosome abnormalities were observed in the terminal stage of the disease in 5 of 9 patients with aneuploid cell lines. The most frequent abnormalities were i(17q) a