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The JAK2V617Ftyrosine kinase mutation in myeloproliferative disorders: Summary of published literature and a perspective

โœ Scribed by Martha Wadleigh; D. Gary Gilliland


Book ID
107540152
Publisher
Current Science Inc.
Year
2006
Tongue
English
Weight
109 KB
Volume
1
Category
Article
ISSN
1558-8211

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Correlations of JAK2โ€“V617F mutation with
โœ Matthaios Speletas; Eirini Katodritou; Chrisoula Daiou; Eudokia Mandala; Emmanou ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 212 KB

Recently, the acquired mutation JAK2-V617F has been described in the majority of patients with myeloproliferative disorders (MPDs). In this study we evaluated its clinical and laboratory correlates in 166 patients with MPDs. The mutation was detected by allele-specific PCR in 119 patients: 81.4% (35