1-Methylisoguanosine was synthesized by a one-pot reaction involving a condensation of 5-amino-l-(L3-D-ribofuranosyl)imidazole-4-carboxamide (1) with methyl isothiocyanate, treatment of the resulting thiourea derivative with DCC furnished 5-(3-methyl-1-ureidol-l-(&gribofuranosyl)imidazole-4-carbonit
The isolation and structural elucidation of a novel naturally-occurring bufadienolide orthoacetate
β Scribed by S. Morris Kupchan; Iliya Ognyanov
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 185 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
In the course of a continuing search for tumor inhibitors of plant origi~ alcoholic extracts of Bersama abyssiniea FresenΒ° (Melianthaeeae) were found to show significant inhibitory activity against cells derived from human carcinoma of the nasopharynx (KB).3, 4 Our earlier report described the isolation
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