A synthesis of the isocoumarin found in the rubromycin class of natural products is reported. The isocoumarin ring system is formed via Heck coupling of a pyruvate synthon with a terephthalic acid derivative followed by an intramolecular acid-catalyzed cyclization. The requisite terephthalic acid pr
β¦ LIBER β¦
The isocoumarin analogue of dicoumarol
β Scribed by N. P. Buu-Hoi; P. Jacquignon; M. Mangane
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 123 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0165-0513
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