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The Involvement of the Apoptosis-Modulating Proteins ERK 1/2, Bcl-xL and Bax in the Resolution of Acute Inflammation in Vivo

✍ Scribed by Deborah A. Sawatzky; Derek A. Willoughby; Paul R. Colville-Nash; Adriano G. Rossi

Book ID: 117970448
Publisher: American Society for Investigative Pathology
Year: 2006
Tongue: English
Weight: 644 KB
Volume: 168
Category: Article
ISSN: 0002-9440
DOI: 10.2353/ajpath.2006.050058

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## Abstract ## Background This study evaluates whether taurolidine, a novel antibiotic agent, induces murine melanoma cell apoptosis in vitro and in vivo. ## Methods Murine melanoma cells (B16 4A5 and B16 F10) were treated with taurolidine (0–100 µM) for 12 and 24 hr. Cell viability and apoptosi